U.S. overdose deaths fell to about 70,000 in 2025 from a peak near 110,000. What the latest CDC data shows and what still worries experts.

Xylazine is a horse sedative now mixed into fentanyl. Why it is called “tranq,” why Narcan cannot reverse it, and why it was named an emerging threat.

Fentanyl is about 50x stronger than heroin, and carfentanil about 100x stronger than fentanyl. What those numbers mean and why 2 mg matters.

They look like real oxycodone or Xanax but contain fentanyl. How counterfeit pills are pressed, what DEA lab tests found, and why you can’t tell by looking.